Abstract
Spirometry is regarded as the only effective method for detecting pulmonary function test (PFT) indices. In this study, a novel impedance pulmonary function measurement system (IPFS) is developed for directly assessing PFT indices. IPFS can obtain high resolution values and remove motion artifacts through real-time base impedance feedback. Feedback enables the detection of PFT indices using only both hands for convenience. IPFS showed no differences in the sitting, supine, and standing postures during the measurements, indicating that patient posture has no effect on IPFS. Mean distance analysis showed good agreement between the volume and flow signal of IPFS (p < 0.05). PFT indices were detected in subjects to differentiate a chronic obstructive pulmonary disease (COPD) patient group from a normal group. The forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC, and peak expiratory flow (PEF) in the COPD group were lower than those in the normal group by IPFS (p < 0.05). IPFS is therefore suitable for evaluating pulmonary function in normal and COPD patients. Moreover, IPFS could be useful for periodic monitoring of existing patients diagnosed with obstructive lung disease.
Highlights
Chronic obstructive pulmonary disease (COPD) is a common and major cause of morbidity, mortality, and airflow obstruction in adults [1,2,3]
Spirometry is the most common type of pulmonary function test (PFT). It can be categorized into two main types: spirometry used in hospitals (e.g., Vmax Encore from VIASYS Healthcare Inc., Hoechberg, Germany) and Peakflow meters (e.g., Piko-1 from Nspire Health Inc, Longmont, CO, USA, or Vitalography copd-6 from Peal Healthcare Solutions Inc, Delaware, USA) used in home environments
We proposed the impedance pulmonary function measurement system (IPFS) for improving upon the disadvantages of existing spirometric and impedance-based methods for the determination of lung function assessment parameters such as
Summary
Chronic obstructive pulmonary disease (COPD) is a common and major cause of morbidity, mortality, and airflow obstruction in adults [1,2,3]. It can be categorized into two main types: spirometry used in hospitals (e.g., Vmax Encore from VIASYS Healthcare Inc., Hoechberg, Germany) and Peakflow meters (e.g., Piko-1 from Nspire Health Inc, Longmont, CO, USA, or Vitalography copd-6 from Peal Healthcare Solutions Inc, Delaware, USA) used in home environments It provides useful diagnosis through measuring and monitoring the lung function of COPD and asthma patients, and for enabling the determination of a therapeutic response to the treatment. EIP was used to determine various lung function parameters, and the obtained results were compared with those obtained by spirometry These studies which are not concerned about PFT indices (e.g., FEV1/FVC, FVC, FEV1, and PEF) focused on respiratory rate detection using a belt(s) or attaching an electrode(s) on the patient’s chest because of low level respiratory signal resolution [17]. The PFT indices obtained by the IPFS can be compared with those obtained by spirometry to enable discrimination between the COPD patient group and the normal group
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