Abstract

The complex mechanisms underlying the development and functioning of the immune system depend on microenvironments in primary and secondary lymphoid organs as regulatory elements. Within a system of millions of different migratory cell types, microenvironments allow cells to meet and to interact with each other. Cellular interaction between specialized cell types and local variations in the concentration and type of soluble mediators control the divergence of immunological reactions within microenvironments.KeywordsPeripheral Lymphoid OrganThymic EpitheliumThymic MedullaThymic MicroenvironmentThymic LobeThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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