Abstract
JDS, ERV, DH, and RDV are paid consultants by WHO/TDR in the development of the strategic business plan for ANDI. TBI is a member of Pfizer's Emerging Markets Customer Advisory Board. The work is supported by the Special Programme for Research and Training in Tropical Diseases, World Health Organization. The funder played no role in the decision to submit the article or in its preparation. Provenance: Not commissioned; externally peer reviewed.
Highlights
The health status of the African population remains behind that of populations in Europe and North America, as well as many other developing regions with similar affluence (Figure S1)
Africa is especially affected by a series of infectious diseases that are responsible for more than half of its disability-adjusted life years (DALYs) and over 6 million deaths per year (Figure S2)
That, in addition to the scant research for several diseases, only 21% of total biomedical research publications and 31% of clinical trials in Africa are related to diseases that account for approximately 50% of the African disease burden (Figure 1)
Summary
N A novel approach to supporting health product research and development (R&D) and access in Africa is urgently needed Successful implementation of such an endeavor requires sustainable capacity, infrastructure, funding, leadership, and an understanding of the status of health R&D in the African continent. Over 170 stakeholders were interviewed across African countries/regions including ministries of health, science and technology, and higher education; national academies of science; pharmaceutical companies and research centers; and networks and universities in South Africa, Nigeria, Egypt, Kenya, and Burkina Faso [6] These interviews identified key factors believed to hamper collaboration, ownership, and leadership of research in Africa. The implementation of ANDI is hoped to help in addressing these challenges
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