Abstract
Triglycidyl isocyanurate (TGIC) is a white solid in powder or granular form. TGIC does not occur naturally in the environment. It is intentionally manufactured and used as a crosslinking agent or hardener to produce polyester powder coatings. TGIC may cause genetic defects. This article presents the method of TGIC determination in workplace air using high-performance liquid chromatography (HPLC) with a diode-array detector (DAD). The method is based on the collection of TGIC present in the air on a polypropylene filter, extraction with acetonitrile, and chromatographic analysis of the solution obtained in this way. The determination was carried out in the reverse-phase system (mobile phase: acetonitrile: water) using an Ultra C18 column. The measurement range is 2 to 40 µg/m3 for a 720 liters air sample. Limit of detection (LOD) is 23 ng/m3 and limit of quantification (LOQ): 70 ng/m3. The method can be used for assessing occupational exposure to TGIC and associated risk to workers’ health.
Highlights
Triglycidyl isocyanurate (TGIC) (CAS No: 2451-62-9) is a solid with a specific gravity of1.2–1.7 g/cm3
It is mainly used for hardening polyester powder paints, which, thanks to TGIC, are characterized by very good functional properties, such as mechanical and chemical resistance, resistance to UV radiation, and maintaining gloss [1,2]
TGIC is a mutagenic substance of category 1B (Muta. 1B)
Summary
Triglycidyl isocyanurate (TGIC) (CAS No: 2451-62-9) is a solid with a specific gravity of1.2–1.7 g/cm. It is mainly used for hardening polyester powder paints, which, thanks to TGIC, are characterized by very good functional properties, such as mechanical and chemical resistance, resistance to UV radiation, and maintaining gloss [1,2]. Repeated or prolonged contact may cause an allergic skin reaction or asthma. It may cause a heritable genetic defect in human reproductive cells [3,4,5,6,7,8,9,10,11,12]. TGIC is a mutagenic substance of category 1B
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