Abstract
In this research, two coated carbon electrodes were constructed and used for the determination of Trifluoperazine hydrochloride (TFPH) drug. The electrodes were constructed by preparing ion-pair for (TFPH) with phosphotungstic acid (PTA) or phosphomolybdic(PMA) acid using di butyl phthalate (DBP) as a plasticizer and poly vinyl chloride (PVC) as a matrix. These electrodes showed good sensitivity towards TFPH. Optimum temperature range (25 - 55 and 25 - 50)o C, limit of detection (4.99 ´ 10-6 and 4.56 ´ 10-6 ) M ,correlation coefficient, (0.9990 and 0.9980), slope (30.67 and 30.26) mV/decade for TFPH-PTA and for TFPH-PMA electrodes respectively.. Optimum pH range (2.7-6.6), the life time (48) days and linear range was (1´10-5 -1´10-2) M for both electrodes. These electrodes were successfully applied for determination of TFPH in pure and pharmaceutical preparations form.
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