Abstract
The values of the thermodynamic ionization constants of the carboxylic (pK=3.30 ± 0.02) and amine (pK=7.00 ± 0.06) groups of cefroxadine were determined at 35.0°C using potentiometric data. The apparent ionization constants of these groups were also determined at 35.0 °C, and at different values of ionic strength.
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