Abstract
This paper presents a sensitive voltametric procedure for the determination of norfloxacin (NF) by a tetraoxocalix[2]arene[2]triazine (TOCT) covalently functionalized multi-walled carbon nanotubes (MWCNTs) modified electrode. The electrochemical sensing of NF was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Through a combination of the excellent selective recognition of TOCT and the outstanding electronic properties of MWCNTs, this electrochemical sensor shows excellent sensitivity and high selectivity for an electrochemical detection of NF. The stripping response is highly linear (R = 0.996) over the NF concentration range of 0.5 - 8.0 μM with the LOD of 0.1 μM. The fabricated sensors were successfully applied for quantitative detection of NF in pharmaceutical formulations and human urine samples. A high anti-interference ability to common interferences and satisfactory results were obtained. This is expected to play a huge potential in the real-time monitoring of NF in clinical applications.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
