Determination of Levels of Some Acute Phase Proteins, Tumor Necrosis Factor-α, Interleukin-1 and Interleukin-6 in Cattle with Trichophythosis

Abstract

Our aim in the study was to determine the levels of some acute phase proteins (APP) and proinflammatory cytokines in cattle with trichophytosis. The animal material of the study consisted of total 30 cattle, 15 with trichophytosis and 15 healthy. The blood samples taken from the Vena jugularis of the cattle in the study into tubes without anticoagulant were centrifuged at 3000 rpm for 15 minutes and their serum samples were obtained. Serum samples were stored at -20 °C until analysis. In the obtained serum samples, haptoglobin, serum amyloid A (SAA), ceruloplasmin, albumin, total protein, tumor necrosis factor-α (TNF-α), interleukin-1 (IL-1) and interleukin-6 (IL-6) analyzes were performed. It was determined that haptoglobin, SAA, TNF-α, IL-1, IL-6 and ceruloplasmin levels were statistically increased in cattle with trichophytosis compared to the control group. In addition, albumin, total protein and globulin values were lower than the control group, but the difference between the groups was statistically insignificant. As a result, it is thought that trichophytosis causes changes in biochemical parameters in cattle, the use of biochemical parameters, especially APPs, will contribute to the diagnosis of trichophytosis and more detailed studies should be done on this subject.