Abstract

Glaucoma is a disease that causes an abnormal increase in intraocular pressure and therefore causes permanent damage to the optic nerves. Early and accurate diagnosis of the disease, known as the most "insidious" disease among eye diseases, is important. In this study, glaucoma prediction application was performed from high-resolution fundus photographs taken from an open-source database. Correlation, energy, homogeneity, contrast and entropy features were extracted from the segmented photographs using the gray-level co-occurrence matrix. Extracted features were divided into 66% test and 33% training after taking their average values. A 3-fold cross-validation was applied to the data and a feedback artificial neural network, classification and regression trees algorithm and k nearest neighbor algorithm were trained using 66% of the data. Classification success was also tested with 33% of test data. As a result, glaucoma and healthy individuals were classified with an average of 86.7% accuracy with the k nearest neighbor algorithm, an average of 87.8% accuracy with the decision trees, and an average of 96.7% accuracy with the artificial neural network algorithm. According to the results obtained, it was seen that glaucoma disease could be detected with high accuracy with the gray-level co-occurrence matrix features of glaucoma disease.

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