Abstract
Ethanol is a common psychoactive substance that has been widely consumed in several parts of the world. Gas chromatography (GC) coupled with flame ionisation detector (FID) has often been used for ...
Highlights
Ethanol is a psychoactive substance used worldwide more frequently in an enormous amount
It is commonly found in forensic toxicology analysis, mainly in post-mortem analysis due to alcohol intoxication which is associated with impairments that frequently lead to violent crimes such as driving under alcohol influence, sexual abuse and fatal accidents(Chun et al, 2016; Kovatsi et al, 2011; Tiscione. et al, 2011)
The capability of the method adopted head space (HS)-gas chromatography (GC)-flame ionisation detector (FID) to determine blood alcohol concentration (BAC) was fit for the intended purpose
Summary
Ethanol is a psychoactive substance used worldwide more frequently in an enormous amount. Blood is the ideal human-based sample used for the analysis of alcohol and other drugs of abuse (Chun et al, 2016). The concentration of ethanol in blood indicates the level of intoxication of an individual and its impact on various human activities. For the above-fortified blood samples, a bias of 8.7 %, 9.4 %, and 0.8 % were obtained respectively which was consistent with the SWGTOX guidelines that establish the maximum acceptable bias should be ±20% at each concentration level. The SWGTOX guidelines explicitly recommended less bias value (±10%) for ethanol analysis, which agreed with the result obtained for the three concentration levels.
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