Abstract
Journal of Cancer Metastasis and Treatment is an open access journal, focusing on basic and clinical studies related to cancer cell, cell biology, oncology, radiation therapy and radiology, obstetrics and gynecology, pediatrics, surgery, hematology, neuro-oncology, etc.
Highlights
Abnormal cell growth can be initiated through inflammation[1]
The cells were treated with the cytokine cocktail from PHA-stimulated Jurkat cells, and a significant increased binding of the lectins could be detected in both cell lines [Figure 2]
In this study we demonstrate that the sialic acid (SA)-expression of RAW 264.7 and MCF-7 cells treated with recombinant cytokines in vitro could be analyzed with the use of SA-imprinted molecularly polymers (SA-MIPs) and flow cytometry
Summary
Abnormal cell growth can be initiated through inflammation[1]. Cancer cells are able to reshape the microenvironment by expression of tumor-promoting chemokines and cytokines[2,3]. Cytokines act as cell regulators of many different biological processes including cell growth, differentiation, metabolism, immunity and inflammation. Cytokines can enhance cancer cell growth by modulating the cellular microenvironment or by affecting the cells directly. Pro- inflammatory cytokines can be oncogenic and thereby inducing elevated levels of pro- invasive factors such as metalloproteinase-2 (MMP-2) and epithelial growth factor
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