Abstract
Clopidogrel (CPD) is prodrug converted endogenously to an unstable active metabolite and an inactive carboxylic acid metabolite. Therefore, CPD is the required analyte in bioequivalence and bioavailability studies. Development and validation of an LC-MS/MS determination of CPD was performed with the aim to be applied for pharmacokinetic analysis. CPD and ticlopidine (TPD, internal standard) were extracted from 200 µL of human plasma with ethylacetate. Chromatographic …
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
