Abstract

BackgroundThe extracts from the leaves of Otostegia integrifolia have been reported to show phytochemical analysis, total flavonoid content, antioxidant and antibacterial activities.ResultsOur results revealed that the total flavonoid content of methanol and ethyl acetate extracts is 416.5 + 0.288 and 248.9 + 0.872 mgAAE/100 g respectively. The two extracts also showed good antioxidant activity as well as weak to moderate antibacterial activity against some bacteria.ConclusionsThe leaf extracts from O. integrifolia showed good total flavonoid content, DPPH radical scavenging activity and antibacterial activity. In addition to this, the extracts also showed the presence of some important compounds by phytochemical analysis.

Highlights

  • The extracts from the leaves of Otostegia integrifolia have been reported to show phytochemical analysis, total flavonoid content, antioxidant and antibacterial activities

  • In Ethiopian traditional medicine, the leaves of O. integrifolia are used for the treatment of several diseases including malaria, for treatment of ophthalmia, as an anti-microbial, antihyperglycemic, and for its anti-oxidant properties used in preventing different kinds

  • In this paper we reported phytochemical analysis, total flavonoid content, antioxidant and antibacterial activities of O. integrifolia leaf extracts

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Summary

Results

Our results revealed that the total flavonoid content of methanol and ethyl acetate extracts is 416.5 + 0.288 and 248.9 + 0.872 mgAAE/100 g respectively. The two extracts showed good antioxidant activity as well as weak to moderate antibacterial activity against some bacteria

Conclusions
Background
Results and discussion
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