Abstract
Schizophyllum commune is well-known, non-consumable split gill mushroom having a variety of nutraceutical properties, due to the presence of various bioactive components. In this study, antidiabetic potency of Schizophyllum commune was evaluated using different extraction solvents. Results revealed the extract of methanol solvent showed high antidiabetic potency (IC50 =50.98 μg/ml), followed by another solvents such as ethanol and hot water extracts respectively. Antidiabetic activity of extracts was compared with standards and positive correlation was observed. In conclusion, based on accumulated data Schizophyllum commune may be used as natural antidiabetic substance and a better alternative to synthetic chemicals. It can be prospective source of potent constituent for fighting against human metabolic disorder.
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