Abstract
Macrosomia has been associated with patient socio-biological determinants and poses increased perinatal risks to mother andchild. The study set out to identify these determinants and assess the risk in a high NIDDM prevalence population. Maternalbiological characteristics and obstetric outcomes of 988 infants weighing more than 4000 gm were statistically compared tosimilar parameters of 15653 infants of lower birth weight. Macrosomia appeared to be commoner in the older obese previouslydiabetic woman aged more than 30 years who had at least one previous pregnancy or miscarriage. Hypertensive disease was anegative correlate. The macrosomic infant was more likely to require an operative intervention for delivery. The delivery wassimilarly more likely to be complicated by shoulder dystocia. The tendency for macrosomia appears to be related to maternalinsulin-resistance metabolic syndrome; while the infant size predisposed to definite intrapartum problems. Effective interventiontherapies to combat excessive fetal growth need to be identified and introduced in clinical practice to prevent the long-termconsequences of macrosomia to the infant.
Published Version
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