Abstract

Detection of Malignant Cases From Focal Liver Masses by Fine Needle Aspiration Cytology and Cell Block

Highlights

  • The spectrum of liver pathologies ranges from hepatitis, cirrhosis, circulatory disorders, hereditary disorders, alcoholic liver disease, liverBiomedica – Vol 37, Issue 1, 2021Detection of Malignant Cases From Focal Liver Masses by Fine Needle Aspiration Cytology and Cell Block abscesses, hepatic cysts and neoplastic lesions.[1]

  • The cell block technique can be used for special stains and immunohistochemistry and can give better morphological details by preserving the architectural patterns.[4]

  • Fine needle aspiration cytology (FNAC) smears adjunct with cell block is likely to improve the diagnosis of liver masses. this study was carried out to determine the diagnostic parameters of FNAC taking cell block as gold standard

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Summary

Introduction

The spectrum of liver pathologies ranges from hepatitis, cirrhosis, circulatory disorders, hereditary disorders (like Hemochromatosis, Wilson’s disease), alcoholic liver disease, liverBiomedica – Vol 37, Issue 1, 2021Detection of Malignant Cases From Focal Liver Masses by Fine Needle Aspiration Cytology and Cell Block abscesses, hepatic cysts and neoplastic lesions.[1]. Liver cancer is the 7th leading cancer among all new cases diagnosed worldwide.[2] Clinically,space-occupying lesions of the liver may present as a solitary, multifocal, diffuse or massive form. It is of utmost importance from the management point of view and poses a strong clinical and histological challenge to differentiate between space-occupying lesions. Fine needle aspiration cytology (FNAC) under ultrasound guidance is a valuable initial technique which is safe, reliable and is used predominantly for diagnosing focal mass lesions.[3] The cell block technique can be used for special stains and immunohistochemistry and can give better morphological details by preserving the architectural patterns.[4] FNAC smears adjunct with cell block is likely to improve the diagnosis of liver masses. this study was carried out to determine the diagnostic parameters of FNAC taking cell block as gold standard. This study was carried out to determine the diagnostic accuracy of fine-needle aspiration cytology in comparison with cell block from the aspirates taken from focal liver masses

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