Abstract

Saliva is a biofluid that is secreted by both the major and minor salivary glands in the oral cavity. It is a crucial component in the digestive process and plays a vital role in maintaining oral health. This fluid is commonly referred to as mirror biofluid, as it indicates the current pathophysiological state of the human body. Over the past decade, saliva has been widely utilized as a diagnostic tool for detecting both oral and systemic diseases. Its non-invasive nature and ease of collection make it an attractive option for healthcare professionals. Saliva is an easily collectible, non-invasive, and safe material that can be utilized as a valuable medium for detecting infectious diseases. The objective of this literature review is to assess the efficacy of oral fluid testing as a diagnostic tool for the detection of HIV. A comprehensive literature review was conducted utilizing PubMed databases, focusing on English language articles and relevant keywords. Saliva-based biomarkers have proven to be an effective means of diagnosing and tracking the progression of HIV, as well as monitoring the efficacy of treatments. This is a significant advancement in the field of HIV research and has the potential to significantly improve patient outcomes

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