Detection of familial hypercholesterolemia in the South of Spain in collaboration wiht the Spanish foundation of familial hypercholesterolemia

Abstract

Background and Aims: Familial hypercholesterolemia (FH) is a genetic disorder with an autosomal dominant Mendelian inheritance pattern. In its heterozygous form (HeFH) it has a prevalence of 1:250. FH accelerates atherosclerotic disease constituting the genetic disorder most frequently associated with premature coronary artery disease (CPD). The prevalence and high risk of developing DBS make FH a public health problem, although the majority of FH patients are underdiagnosed and undertreated.