Abstract
The ehrlichiae are small Gram-negative obligatory intracellular bacteria in the family Anaplasmataceae. Ehrlichiae infection ln an accidental host may result in severe fatal diseases such as human monocytotropic ehrlichiosis (HME), an emerging, tick-borne disease. Using Ehrlichia muris as a model organism, here I show that E. muris can infect bone marrow-derived dendritic cells and macrophages. The ehrlichial infection can be detected by polymerase chain reaction in cultured dendritic cells and macrophages as well as experimentally infected animals.
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