Abstract
The purpose of this study was to evaluate the detectability of corona enhancement around the hypervascular hepatocellular carcinoma (HCC) by dual-phase cone-beam computed tomography during hepatic arteriography (CBCTHA). Dual-phase CBCTHA was performed for 71 HCC lesions (mean±SD 1.7±0.9cm), including seven presenting a nodule-in-nodule appearance and nine hypervascular pseudolesions. The first scan was performed during injection of 30-40ml half-diluted contrast material at a rate of 1.5-2ml/s through the hepatic artery. Scanning was initiated 7s after the beginning of contrast material injection. The second scan was started 30s after the end of the first scan. Detectability of corona enhancement on second-phase CBCTHA was evaluated. Thickness of corona enhancement was also analyzed as thin (≤2mm) or thick (>2mm). Corona enhancement was detected in 63 (88.7%) of 71 tumors (1.8±0.9cm), but it was not detected in eight tumors (1.0±0.2cm). Thin corona enhancement was seen in 18 tumors (1.2±0.5cm), and thick corona enhancement was seen in 45 tumors (2.0±0.9cm). There was a significant difference in tumor diameter between tumors with and those without corona enhancement (P=0.0157) and between thin and thick corona enhancement (P=0.001). In all seven early-stage tumors, corona enhancement was demonstrated around the hypervascular focus within the hypovascular tumor portion. None of the nine pseudolesions showed any corona enhancement. Dual-phase CBCTHA depicted corona enhancement in 88.7% of hypervascular HCC lesions. This technique may improve the diagnostic accuracy of HCC.
Published Version
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