Abstract
Introduction: So far, a tumor-specific marker for nephroblastoma has not been described. A sensitive and specific liquid biopsy test of diagnosing tumor occurrence within the peripheral blood could possibly contribute to an improved prognosis of affected patients. Different reactions of the immune system to tumors have been observed so far; these reactions include as a very early step phagocytosis of tumor cells by macrophages. The Epitope-Detection in Monocytes (EDIM blood test) allows detection of intracellular tumor-protein epitopes in peripheral blood macrophages after phagocytosis of tumor cells or even compounds.
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