DETECTION OF ANTIBIOTICS SENSITIVITY OF SALMONELLA TYPHI IN WASIT PROVINCE OF IRAQ

Abstract

Background: Salmonella typhi was food born infectious bacterial agent can transfer to human by water or food contaminated and causing disease in both gender and also infected healthy and immunocompromised patients enteric fever stay to remain as a major public health problem. Objective: current study was design to isolate Salmonella typhi from blood and them detecting its by using different biochemical tests like API20E, and them tested isolated pathogen to different antibiotics in which commonly used in treatment through antibiotic sensitivity test. Methods: in this study a total of 800 blood samples were collected randomly from patients with different ages and gender suffered from clinical symptoms of typhoid fever in which attended to al-karma teaching hospital in alKut-Waist government/ Iraq, after diagnosis of them appeared that 72 patients (9%) of them infected with Salmonella typhi, them used appropriate statistical methods to analysis many results, after that detected of antimicrobial activity of these pathogenic bacteria by using different antibiotics that commonly used in treatment of these disease, the results of this test show that all isolates appeared sensitive to imipenem followed by ciprofloxacin (95.8%) them Ceftriaxone(93.7%), Co-trimoxazole(83.2%), Chlormophenicol (71.5%), Ampicillin(70.51%) and last one was nalidixic acid (68.5%). Aims: this study was design to detect ratio of infection with this pathogen in Waist province in Iraq and also discovered the most suitable antibiotics in treatment of its. Keywords: