Abstract

The Objectives: safety of blood products is one of the major issues in the area of transfusion medicine. In previous study we found that hepatitis B virus was epidemic in some of Basrah medical institutions to assess the prevalence of anti-HBc and anti-HBs antibodies in serum samples of healthy blood donors negative for both HBsAg and anti-HCV in the Central Blood Bank, Basrah-Iraq. Results: 204 serum samples negative for both HBsAg and anti-HCV collected from healthy blood donors were tested for the presence of HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc by using rapid chromatographic immunoassay. Of the 204 samples tested, 13 (6.37%) of the HBsAg negative blood samples were found to be positive for anti-HBc. 3(1.47%) out of 13 anti-HBc positive were found positive for anti-HBs. Conclusion: detection of anti-HBc and anti-HBs antibodies were more important than other markers in detection of latent Hepatitis B virus infection.

Highlights

  • Hepatitis B (HBV) is an indolent disease that seldom causes symptoms until complications of cirrhosis and liver cancer occur.[1]

  • In previous study[8] we found that the the world's population have had contact with or hepatitis B virus was really societyare carriers of the HBV

  • This corresponds to an threatening and epidemic in some of the Basra estimated 350 million HBV carriers and medical institutions in dialysis and around one million persons die of HBV-related oncology units

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Summary

Introduction

Hepatitis B (HBV) is an indolent disease that seldom causes symptoms until complications of cirrhosis and liver cancer occur.[1]. Hepatitis B (HBV) is an indolent disease that seldom causes symptoms until complications of cirrhosis and liver cancer occur.[1] It is estimated that 40% of infections but lost detectable anti-HBs antibodies.

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