Abstract
BackgroundMagnetic induction measurement (MIM) is a noninvasive method for the contactless registration of respiration in newborn piglets by using measurement coils positioned at the bottom of an incubator. Acute pulmonary problems may be determinants of poor neurological and psychomotor outcomes in preterm infants. The current study tested the detection of pulmonary ventilation disorders via MIM in 11 newborn piglets.MethodsSix measurement coils determined changes in magnetic induction, depending on the ventilation of the lung, in comparison with flow resistance. Contactless registration of induced acute pulmonary ventilation disorders (apnea, atelectasis, pneumothorax, and aspiration) was detected by MIM.ResultsAll pathologies except aspiration were detected by MIM. Significant changes occurred after induction of apnea (three coils), malposition of the tube (one coil), and pneumothorax (three coils) (p ≤ 0.05). No significant changes occurred after induction of aspiration (p = 0.12).ConclusionsMIM seems to have some potential to detect acute ventilation disorders in newborn piglets. The location of the measurement coil related to the animal’s position plays a critical role in this process. In addition to an early detection of acute pulmonary problems, potential information pointing to a therapeutic intervention, for example, inhalations or medical respiratory analepsis, may be conceivable with MIM in the future.ImpactMIM seems to be a method in which noncontact ventilation disorders of premature and mature infants can be detected.This study is an extension of the experimental setup to obtain preliminary evidence for detection of respiratory activity in neonatal piglets. For the first time, MIM is used to register acute ventilation problems of neonates.The possibility of an early detection of acute ventilation problems via MIM may provide an opportunity to receive patient-side information for therapeutical interventions like inhalations or medical respiratory analepsis.
Highlights
Apneas or disorders of the respiratory system, such as pneumothorax or tube shifts, are clinically detected by alarm-triggering respirators, pulse oximeters, and heart rate monitors
Because the registration of the signal occurred with six different measurement coils (Fig. 2), analysis of each measurement coil showed that coil number 4, followed by coil number 2, and coil number 6 were the ones that registered a change in the level of the amplitude after induction of all four pathologies (p ≤ 0.05; Table 3)
In our study, we could extend our established newborn animal model with induced pathologies. These pathologies were registered by standard monitoring with pulse oximetry, ECG, and X-ray
Summary
Magnetic induction measurement (MIM) is a noninvasive method for the contactless registration of respiration in newborn piglets by using measurement coils positioned at the bottom of an incubator. Contactless registration of induced acute pulmonary ventilation disorders (apnea, atelectasis, pneumothorax, and aspiration) was detected by MIM. ● The possibility of an early detection of acute ventilation problems via MIM may provide an opportunity to receive patient-side information for therapeutical interventions like inhalations or medical respiratory analepsis. Capacitive coupling, for example, to replace the cable-bound electrocardiogram (ECG) on the neonatal intensive care unit (NICU) has been investigated.[3] Recent reviews focus on neonatal heart rate monitoring.[4,5] Regarding the respiratory rate, infrared thermography has demonstrated the potential for application as it allows to monitor the breathing rate of the neonate and the surface temperature distribution.[6] Another method offering such noninvasive, contactless monitoring is the so-called “magnetic induction measurement” (MIM).
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
