Abstract
An efficient ultrasonic synthesis of structurally diverse Pyridine-2,6-dithiazole/ dioxazole analogues were designed and achieved by ultrasonic irradiation techniqueas well as by conventional method. The advantages of this eco-friendly ultrasonic irradiation method over conventional method are excellent yields, no metal catalyst, less toxic solvents, simple workup, no chromatographic column purifications. The precursor S-6 and S-16 and their Schiff base derivatives S-10 to S-15 and S-17 to S-22 were characterized by spectral means, found consistent for expected structure. To check their biological potential molecular docking and invitro antimicrobial studies were also performed.
Published Version
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