Abstract
Abnormal intracellular hydrogen peroxide (H2O2) concentration is related to cancer, cardiovascular, cerebrovascular diseases and other diseases. A novel H2O2 fluorescent probe (BBS) was designed and synthesized. The fluorescence intensity shows good linear relationship with the concentration of H2O2 (0–40 μM), and the detection limit is 132 nM. The response mechanism of probe BBS was verified and analyzed by UV–Vis spectra, titration spectra and density functional theory (DFT) on Gaussian 09 programme. BBS can be used for bioimaging in living cells.
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