Abstract
A new library of various types of aryl pyrimidine-thiadiazoles (8a-j) have been synthesized and their structures characterized by analytical techniques. Further, all compounds were subjected to in vitro anticancer activity towards four human cancer cell lines such as PC3 & DU-145 (Prostate cancer), A459 (lung cancer) and MCF-7 (breast cancer) by using MTT assay and etoposide used as reference compound. Most of the tested compounds displayed excellent to moderate activity. Among them, compounds 8a, 8d, 8e, 8f and 8g showed more potent activity. In which one compound 8e showed remarkable activity.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
