Abstract

In 1957 the original continuous flow analysers performed urea estimations at 20 samples/hr. Multichannel analysers were later introduced and by 1968 it was possible to analyse 60 samples/hr for 12 parameters, 4 of which were blanked. This paper described what was necessary to improve this technique to analyse 150 samples/hr, to perform 20 analyses on each sample, to require a maximum sample of 500 μl for these 20 tests and to require 6 ml of reagents for these 20 tests. The following improvements were noticed :— (1) Hydraulics (a) More extensive miniaturization, (b) variation in the use of bubbles, (c) flow cell changes (2) Modified chemical techniques (a) ion selective electrodes, (b) multipoint enzyme analysis. (3) The use of a controlling computer to monitor all estimations continuously.

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