Abstract
The present article discusses the functionalization of psyllium by binary monomer mixture of acrylamide and 2-acrylamido-2-methylpropane sulphonic acid to develop the new drug delivery devices. These were characterized by SEMs, FTIR, TGA and swelling studies. The swelling kinetics of the hydrogels and release dynamics of drug (indinavir sulphate) from the drug loaded hydrogels has been studied for the evaluation of the swelling and drug release mechanism respectively. The release of the drug from the hydrogels occurred through Fickian diffusion mechanism in pH 2.2 buffer. The antiviral activity of indinavir sulphate for AIDS, anti-diarrhoeal action of psyllium and inhibitory effects of sulphated polymers on STD pathogens will enhance the potential of the drug delivery devices.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
