Abstract
In this study, we design and present a five-fold digital slit-lamp microscope (DSLM) with built-in photographic lens and CCD. The initial structures of the front objective, Galilean telescope system, and photographic lens are systematically investigated and discussed in the design. A progressive optimization process is employed in the non-coaxial system design after the coaxial system achieves high performance. The analysis of spot diagrams and the modulation transfer function (MTF) show that this DSLM optical system achieves quasi-diffraction-limited performance and enables high-quality imaging for ophthalmic examination. Furthermore, tolerance analysis of this optical system is also performed, which provides a theoretical basis for machining and assembly. This design provides an idea for the design of a digital-zoom microscope in biomedical imaging instruments.
Highlights
As one of the most advanced analysis instruments in biomedical science, the microscope has been rapidly developed in recent years [1,2,3]
digital slit-lamp microscope (DSLM) contribute to transmitting images for remote diagnosis
One light is delivered to a tube lens and eyepiece, and the is sent to a built-in photographic lens and CCD for imaging
Summary
As one of the most advanced analysis instruments in biomedical science, the microscope has been rapidly developed in recent years [1,2,3]. The slit-lamp microscope (SLM), invented by Allvar Cullstrand, is most useful in clinical ophthalmology [4,5]. The traditional SLM relies only on visual observation and needs manual mapping to record the signs of disease, which is inconvenient and unreliable. With the advent of cameras and the progress of digital technology, the digital slit-lamp microscope (DSLM) is favored by researchers in the field of ophthalmology due to the unique advantages of high resolution, quick acquisition, and storage of image information [10]. In order to quickly and accurately determine the signs of disease, capturing high-quality and high-resolution images is essential in telemedicine consultation. The main design of a conventional SLM does not include an image acquisition module. Yen et al reported a method of image acquisition from
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