Abstract
The human embryonic stem cell line RCe008-A (RC-4) was derived from a blastocyst voluntarily donated as unsuitable and surplus to fertility requirements following ethics committee approved informed consent under licence from the UK Human Fertilisation and Embryology Authority. The cell line shows normal pluripotency marker expression and differentiation to ectoderm and mesoderm in vitro. It has a mixed 46XX/45X female karyotype and microsatellite PCR identity and blood group typing data is available.
Highlights
RCe008-A (RC-4) was derived from a fresh blastocyst that was surplus to requirement or unsuitable for clinical use
A microsatellite PCR profile has been obtained for the cell line and blood group genotyping gave the blood group AO1 (Table 2)
Derivation of hESC from surplus to requirement and failed to fertilise/develop embryos was approved by The Scotland A Research Ethics Committee and local ethics board at participating fertility clinics and conducted under licence no
Summary
Citation for published version: De Sousa, P, Tye, B, Bruce, K, Dand, P, Gardner, J, Downie, JM, Bateman, M & Courtney, A 2016, 'Derivation of the human embryonic stem cell line RCe008-A (RC-4)', Stem Cell Research, vol 16, no. 3, pp. 607-610. https://doi.org/10.1016/j.scr.2016.02.039 General rights Copyright for the publications made accessible via the Edinburgh Research Explorer is retained by the author(s) and / or other copyright owners and it is a condition of accessing these publications that users recognise and abide by the legal requirements associated with these rights.
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