Abstract

‌BackgroundWomen are at a higher risk for depression progression, especially during pregnancy. The current study purposed to investigate depression, anxiety, and stress levels of pregnant mothers in the initial stage of the COVID-19 infection in the southwest of Iran.MethodsThis cross-sectional study was conducted during March and April, 2020, in Shiraz, Iran. Pregnant mothers registered in maternity clinics affiliated with Shiraz University of Medical Sciences were included. An online self-administered checklist was used. It included socio-demographic, obstetric and medical histories, and the short form of the Depression Anxiety Stress Scales (DASS-21) to evaluate depression, anxiety, and stress. A p-value < 0.05 was considered significant.ResultsIn total, 540 pregnant mothers answered the questionnaire. 83.5% had no comorbidity. Abnormal depression scores were significantly higher in those who had no insurance (OR = 2.5) and in those with poor self-rated health (SRH) (OR = 27.8). Pregnant mothers with lower SRH and two or more comorbidities had a higher chance of having an abnormal level of anxiety subscale (6.9, 3.7 times, retrospectively).ConclusionThe results revealed that an abnormal level of depression was associated with SRH and medical insurance status. Moreover, the number of comorbidities and poor SRH significantly increased the chance of achieving abnormal anxiety levels in pregnant mothers during the COVID-19 pandemic.

Highlights

  • In late December 2019, Chinese healthcare facilities in Wuhan, Hubei, China reported numerous pulmonary infection cases with an unknown type, named coronavirus disease 2019 (COVID-19) [1, 2]

  • The results of this study revealed that pregnant women repeated abnormal depression and anxiety levels in the initial stage of the COVID-19 pandemic

  • They further showed that pregnant mothers who had two or more comorbidities and those with lower self-rated health (SRH) had a higher chance of having an abnormal anxiety level

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Summary

Introduction

In late December 2019, Chinese healthcare facilities in Wuhan, Hubei, China reported numerous pulmonary infection cases with an unknown type, named coronavirus disease 2019 (COVID-19) [1, 2]. Previous studies revealed the remarkable impacts of infectious disease outbreaks such as severe acute respiratory syndrome (SARS) on psychological distress, including depression and anxiety in pregnant mothers [9]. The children of mothers who experience high psychological distress during pregnancy are more likely to have cognitive and behavioral problems and their communication skills are significantly affected [10, 11]. Few studies have reported psychological distress in pregnant mothers during the COVID-19 pandemic [12,13,14]. This study aimed to investigate the predicting factors of depression, anxiety, and stress levels of pregnant mothers in the initial stage of the COVID-19 infection in the southwest of Iran

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