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Abstract
BackgroundThe aim of the present study was to compare the presence of psychiatric disorders in people with hyperthyroidism and euthyroid patients attending the Endocrinology Outpatient Department at the Shri Maharaja Hari Singh Hospital in Kashmir, India. Seventy-five patients with hyperthyroidism and an equal number of euthyroid patients participated in the study. Participants were selected using stratified random sampling. All patients were female. There was no significant difference between the two groups in terms of demographic features. Hormonal screening was performed by immunoassay and haemagglutination method. For the mental health assessment, the Mini-International Neuropsychiatric Interview (MINI), Hamilton Depression Rating Scale [HAM-D], and Hamilton Anxiety Rating Scale [HAM-A] were used.ResultsThere was a higher prevalence of psychiatric disorders among the hyperthyroidism group (60% versus 34.7%). In particular, there was a higher prevalence of major depressive disorder, suicidality, generalised anxiety disorder, panic attacks, and agoraphobia. In some cases, the prevalence of a psychiatric disorder diminished after endocrinological treatment.ConclusionsScreening patients with hyperthyroid disorders for psychiatric symptoms and disorders, and providing timely care when necessary, can go a long way in improving the quality of life of this population. It is imperative to establish routine screening and timely care of mental health symptoms and disorders in patients with hyperthyroidism.
Highlights
The aim of the present study was to compare the presence of psychiatric disorders in people with hyperthyroidism and euthyroid patients attending the Endocrinology Outpatient Department at the Shri Maharaja Hari Singh Hospital in Kashmir, India
Patients with hyperthyroidism were treated by surgery, antithyroid drug (ATD) medication, or radioactive iodine (RAI)
Of the total of participants with hyperthyroidism, 4% presented suicidality, a number that dropped to almost 0% after endocrinological treatment
Summary
The aim of the present study was to compare the presence of psychiatric disorders in people with hyperthyroidism and euthyroid patients attending the Endocrinology Outpatient Department at the Shri Maharaja Hari Singh Hospital in Kashmir, India. Seventy-five patients with hyperthyroidism and an equal number of euthyroid patients participated in the study. Hyperthyroidism is one of the most common thyroid disorders. Hyperthyroidism can often manifest with symptoms consistent with mental illnesses; plus, it is not uncommon for people with hyperthyroidism to meet psychiatric disorders’ diagnostic criteria [1, 2]. People with hyperthyroidism will likely present symptoms such as tension and other autonomic. Various psychiatric disorders have been associated with hyperthyroidism. Over 150 years ago, Basedow had already described a manic psychosis illness in a patient with exophthalmic goitre [4]. Psychotic disorders are an uncommon presentation of hyperthyroidism [4–6]. Symptoms of anxiety and depression, on the other hand, are more common [7, 8], as well as increased scores on depression and anxiety self-rating scales [9]
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