Abstract
in the heterozygote for the optimal allele by switching on a diploid, symmetric, sharply-peaked landscape. The increase in the relative density of the reversal allele for h 1 is found to be a linearly increasing function of time unless an equilibrium state in a diploid, symmetric, sharply-peaked landscape is reached and the increase in the relative density of the reversal allele for h > 1 is found to be a rapidly increasing function of time because the marginal tness for the reversal allele is greater than the marginal tness for the optimal allele. The crossing time for h < 1 is found to diverge at the critical tness parameter, which is the characteristic of the haploid quasispecies model in the asymmetric, sharply-peaked landscape. The crossing time for h = 1 is found to scale as a power law in the tness parameter, which is the characteristic of the haploid quasispecies model in the symmetric, sharply-peaked landscape. The crossing time for h = 1:25 is also found to stop increasing and to start decreasing at a tness parameter approximately six times larger than the mutation rate although the tness parameter increases.
Published Version
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