Abstract
Antibiotics are widely used in dental caries and another dental related issues, both for therapeutic and prophylactic reasons. Unfortunately, in recent years the use of antibiotics has been accompanied by the rapid emergence antimicrobial resistance. Dental caries and periodontal diseases are historically known as the top oral health burden in both developing and developed nations affecting around 20–50% of the population of this planet and the uppermost reason for tooth loss. Dental surgeons and family practitioners frequently prescribed antimicrobials for their patients as outpatient care. Several studies reported that antibiotics are often irrationally- and overprescribed in dental diseases which is the basis of antimicrobial resistance. The aim of this review is to evaluate the use of antibiotics in dental diseases. Almost certainly the promotion of primary oral health care (POHC) in primary health care program especially among the least and middle-income countries (LMIC) may be the answer to ensure and promote rational dental care.
Highlights
Penicillin was the first antimicrobial agent discovered in 1928 [1] and the first patient was treated with this newly discovered medicine in 1942 [2]
Dental caries and periodontal diseases are historically known as the top oral health burden in both developing and developed nations affecting around 20–50% of the population of this planet, and is the uppermost reason for tooth loss [14,15,16]
This study examined in further detail 25,020 children and reported that girls possess better oral and dental health when compared to boys regarding decayed missing and filled primary teeth (DMFT)
Summary
Penicillin was the first antimicrobial agent discovered in 1928 [1] and the first patient was treated with this newly discovered medicine in 1942 [2]. World War II promoted extraordinary cooperation between two nations situated either side of the Atlantic, United States and Great Britain, resulting in unbelievably efficient bulk production of penicillin by 1943 [1,3]. Dutch scientists during post World War II developed a new method of producing penicillin which was marketed in 1946, and ensured mass production of penicillin for the medicine market and reduced the cost of treatment [3,4]. Antibiotics have transformed modern medicine and countless lives have been saved through their use over the years. The use of this miracle medicine has been accompanied by the rapid emergence of resistant strains due to the unstoppable spread of antibiotic resistance genes among the microbial community [5,6]
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