Abstract
Background: Dengue fever is endemic in Peru. The epidemic potential for dengue transmission north of Lima city has spread alarmingly in the last four years. A dengue outbreak occurs during March to June 2009 in three districts of Lima. The 2005 and 2007 outbreaks of dengue fever occurred in these districts only one circulating serotype in each outbreak. Epidemiological investigation was conducted to determine the distribution of cases, serotype circulation, symptoms and signs of dengue fever in order to identify transmission and epidemic control measures. Methods: Analysis of cases of the outbreak investigation conducted by the network of epidemiology at the Department of Health V Lima City. The information was collected and processed through software NotiSp. Suspected case was considered a person with a history of fever for 2 to 7 days and two or more of the following symptoms: headache, retroocular, myalgia, arthralgia, rash and hemorrhagic manifestations residing in the districts of Carabayllo, Comas and Independence. The cases were registered in epidemiological records, blood samples were taken to determine seroconversion and identification of circulating serotypes. Results: Of 552 cases suspects, 148 (26.8%) were positive for IgM antibody detection of specific dengue indicating primary infection and 99 cases were obtained by PCR serotypes: DEN-3 (74%), DEN-1 (24%) and DEN-4 (2%). Most cases (45%) were adults between 20 and 59 years of age. The median age was 34 years. Women were more affected than men (56% and 44% respectively). The most frequent symptoms were fever (95%), headache (90%), body ache (86%), bone pain (75%) and pain retroocular (70%). The outbreak investigation revealed a cluster of four clusters that could be because they have areas favourable for breeding of the vector, such as presence of disposable plastic containers, clearing rocks, water shortages and the migration of people to Lima from dengue endemic areas. Conclusion: The outbreak investigation confirmed the presence of dengue as an emerging public health problem in Lima, identifying the co-circulation of three serotypes, demonstrating dengue epidemiological changes, so it is important to strengthen surveillance actions epidemiological and vector control in these areas during the coming years. Abstracts for SupplementInternational Journal of Infectious DiseasesVol. 14Preview Full-Text PDF Open Archive
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