Demonstration of effectiveness and tolerability of terconazole 80-mg vaginal suppositories (3 days) versus terconazole 240-mg vaginal suppositories (1 day) versus clotrimazole 200-mg vaginal tablets (3 days) in non-pregnant women with vulvovaginal candidosis.

Abstract

Vulvovaginal candidosis occurs frequently in women of reproductive age. Local therapy with imidazole derivatives is very effective and should be preferred to oral therapy. In a multicentre trial in Holland and Belgium a single-dose treatment with a 240-mg terconazole vaginal suppository proved as effective as a 3-day treatment with vaginal suppositories containing 80 mg terconazole or a 3-day treatment with vaginal tablets containing 200 mg clotrimazole.