DEMOGRAPHIC AND CLINICAL PROFILE OF DEVELOPMENTAL ODONTOGENIC CYSTS IN A BRAZILIAN POPULATION

Abstract

Odontogenic cysts (OCs) are the most frequent lesions of gnathic bones and present with unique clinical findings and diverse biological behavior. Objective: To describe the demographic and clinical characteristics of developmental OCs diagnosed in a pathologic anatomy service. Study design: Through retrospective and descriptive analyses, data referring to age, sex, size, location, and radiographic characteristics were obtained from the biopsy request forms in the period 2002-2018. Results: A total of 135 cases of developmental OC were identified, of which 48% (n = 65) were odontogenic keratocyst (OKC), 36% (n = 49) dentigerous cyst (DC), 9% (n = 12) calcifying odontogenic cyst (COC), 3% (n = 4) gingival cyst of adult, and 1.48% (n = 2) glandular odontogenic cyst (GOC). Lateral periodontal cyst (LPC), botryoid odontogenic cyst (BOC), and orthokeratinized odontogenic cyst (OOC), were 1% (n = 1) each. Mean age of the patients was 30.6 years, with no predilection for sex. OKC, COC, and GOC showed the largest sizes, with averages of 2.92 cm, 2.67 cm, and 4.0 cm, respectively. The posterior mandible was affected more often (59%; n = 80). Radiographically, 41.5% exhibited a unilocular radiolucent appearance. Conclusion: DC and OKC were more frequent in this study. Developmental OCs predominated in the posterior mandible and the most aggressive lesions were large in sizes. Odontogenic cysts (OCs) are the most frequent lesions of gnathic bones and present with unique clinical findings and diverse biological behavior. Objective: To describe the demographic and clinical characteristics of developmental OCs diagnosed in a pathologic anatomy service. Study design: Through retrospective and descriptive analyses, data referring to age, sex, size, location, and radiographic characteristics were obtained from the biopsy request forms in the period 2002-2018. Results: A total of 135 cases of developmental OC were identified, of which 48% (n = 65) were odontogenic keratocyst (OKC), 36% (n = 49) dentigerous cyst (DC), 9% (n = 12) calcifying odontogenic cyst (COC), 3% (n = 4) gingival cyst of adult, and 1.48% (n = 2) glandular odontogenic cyst (GOC). Lateral periodontal cyst (LPC), botryoid odontogenic cyst (BOC), and orthokeratinized odontogenic cyst (OOC), were 1% (n = 1) each. Mean age of the patients was 30.6 years, with no predilection for sex. OKC, COC, and GOC showed the largest sizes, with averages of 2.92 cm, 2.67 cm, and 4.0 cm, respectively. The posterior mandible was affected more often (59%; n = 80). Radiographically, 41.5% exhibited a unilocular radiolucent appearance. Conclusion: DC and OKC were more frequent in this study. Developmental OCs predominated in the posterior mandible and the most aggressive lesions were large in sizes.