Dehydrogenative Annulation of Heterocycles: Synthesis of Fused Heterocycles

Abstract

The present chapter focuses upon transition metal-catalyzed cross-dehydrogenative coupling (CDC) reactions, resulting in the formation of fused heterocycles from heterocyclic scaffolds. The concept of C–H bond activation employed in these transformations is elaborately described, with representative examples and detailed mechanistic insights. Formation of C–C/C–N/C–B bonds arising from CDC reactions is represented individually under distinct sub-headings, with the inclusion of both intra- and intermolecular reactions. Hence a concise overview regarding the diverse aspects of transition metal-catalyzed CDCs is provided herein to assist in effortless comprehension of the term, initially coined by Prof. Li.