Abstract

<p>A review of the definition and classification of heart failure, updated since the recent 2016 European Society of Cardiology guidelines for the diagnosis and treatment of acute and chronic heart failure. Heart failure is defined by the European Society of Cardiology (ESC) as a clinical syndrome characterised by symptoms such as shortness of breath, persistent coughing or wheezing, ankle swelling and fatigue, that may be accompanied by the following signs: jugular venous pressure, pulmonary crackles, increased heart rate and peripheral oedema. However, these signs may not be present in the early stages and in patients treated with diuretics. When apparent, they are due to a structural and/or functional cardiac abnormality, leading to systolic and/or diastolic ventricular dysfunction, resulting in a reduced cardiac output and/or elevated intra- cardiac pressures at rest or during stress. According to the most recent ESC guidelines the initial evaluation of patients with suspected heart failure should include a clinical history and physical examination, laboratory assessment, chest radiography, and electrocardiography. Echocardiography can confirm the diagnosis. Beyond detecting myocardial abnormality, other impairments such as abnormalities of the valves, pericardium, endocardium, heart rhythm, and conduction may be found. The identification of the underlying aetiology is pivotal for the diagnosis of heart failure and its treatment. The authors review the definitions and classifications of heart failure.</p><p> </p>

Highlights

  • Heart failure is defined by the European Society of Cardiology (ESC) as a clinical syndrome characterised by symptoms such as shortness of breath, persistent coughing or wheezing, ankle swelling and fatigue, that may be accompanied by the following signs: jugular venous pressure, pulmonary crackles, increased heart rate and peripheral oedema.[1]

  • The recent ESC guidelines [1] have provided diagnostic criteria for a newly defined group HFmrEF standing for Heart Failure with mid-­range Ejection Fraction

  • In 2004, a U.S consensus statement defined advanced heart failure as a “state in which patients have significant cardiac dysfunction with marked symptoms of dyspnoea, fatigue, or symptoms relating to end-­organ hypoperfusion at rest or with minimal exertion despite maximal medical therapy” [28]

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Summary

Introduction

Heart failure is defined by the European Society of Cardiology (ESC) as a clinical syndrome characterised by symptoms such as shortness of breath, persistent coughing or wheezing, ankle swelling and fatigue, that may be accompanied by the following signs: jugular venous pressure, pulmonary crackles, increased heart rate and peripheral oedema.[1] these signs may not be present in the early stages and in patients treated with diuretics When apparent, they are due to a structural and/ or functional cardiac abnormality, leading to systolic and/or diastolic ventricular dysfunction, resulting in a reduced cardiac output and/or elevated intra-­cardiac pressures at rest or during stress [2,3]. The recent ESC guidelines [1] have provided diagnostic criteria for a newly defined group HFmrEF standing for Heart Failure with mid-­range Ejection Fraction Such an ‘intermediate group’ or ‘grey area’ presents as mild systolic dysfunction, with a LVEF in the range of 40–49%. Episodes of fluid retention (pulmonary and/or systemic peripheral hypoperfusion congestion, peripheral edema) and/or reduced cardiac output at rest (peripheral hypoperfusion)

Objective evidence of severe cardiac dysfunction
Severe impairment of functional capacity
Presence of all the previous features despite “attempts to optimise” therapy
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