Defining Psoriasis Remission Based on Histopathologic and Molecular Criteria: A Systematic Literature Review

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Tremendous progress has been made in the treatment of psoriasis owing to the successful use of translational medicine in the last two decades (Reid and Griffiths, 2020). Using targeted biologics, nearly 90% of patients with psoriasis can achieve a clear or almost clear response (Hawkes et al., 2018). Thus, it is timely to start thinking about the use of advanced endpoints for psoriasis clinical trials to drive the next level of innovation toward disease remission and, even more ambitiously, a cure.