Abstract
Background: The relationship between Helicobacter pylori infection and iron metabolism has not been well studied in Japan. We examined the association of H. pylori infection and its eradication to ...
Highlights
Helicobacter pylori (H. pylori) is the main cause of gastric or duodenal ulcers, gastric cancer, and atrophic gastritis (Asaka et al, 2010; Malfertheiner et al, 2017)
We examined the association between H. pylori infection and iron metabolism, with consideration of the daily intake of iron and vitamin C, in a Japanese population taking a health survey to assess the possibility of H. pylori eradication for the improvement of iron metabolism in Japan
To date, the relationship between H. pylori infection and iron metabolism has not been fully investigated in Asian populations, for adults (Hudak et al, 2017)
Summary
Helicobacter pylori (H. pylori) is the main cause of gastric or duodenal ulcers, gastric cancer, and atrophic gastritis (Asaka et al, 2010; Malfertheiner et al, 2017). In Japan, only one study examined the effect of H. pylori eradication on iron metabolism (Sato et al, 2015). The relationship between Helicobacter pylori infection and iron metabolism has not been well studied in Japan. H. pylori stool antigen was tested and serum antibody titer and serum iron, ferritin and pepsinogen levels were estimated Subjects reported on their daily intake of the diets to calculate daily intake of iron and vitamin C. Among the H. pylori-infected patients surveyed in 2012, 177 patients completed the same health survey in 2014 For these patients, the change of daily intake of iron and vitamin C and serum iron and ferritin levels were examined. Eradication of H. pylori increased the serum level of ferritin without corresponding changes in the intake of iron and vitamin C
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