Abstract

The scaling index method was used in order to analyze atomic force microscopic images of double-stranded DNA (plasmid PUC 8) adsorbed to mica. With this algorithm, the image can be decomposed into constituents of different dimensionality, i.e., point-like, thread-like, and area-like structures, and residual noise. Special focus is on the evaluation of this method for the future automated analysis of binding events of DNA-specific proteins.

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