Deciphering Bisphenol A degradation by Coelastrella sp. M60: unravelling metabolic insights through metabolomics analysis

Abstract

Microalgae, owing to their efficacy and eco-friendliness, have emerged as a promising solution for mitigating the toxicity of Bisphenol A (BPA), a hazardous environmental pollutant. This current study was focused on the degradation of BPA by Coelastrella sp. M60 at various concentrations (10-50 mg/L). Further, the metabolic profiling of Coelastrella sp. M60 was performed using GC-MS analysis, and the results were revealed that BPA exposure modulated the metabolites profile with the presence of intermediates of BPA. In addition, highest lipid (43%) and pigment content (40%) at 20 and 10 mg/L of BPA respectively exposed to Coelastrella sp. M60 was achieved and enhanced fatty acid methyl esters recovery was facilitated by Cuprous oxide nanoparticles synthesised using Spatoglossum asperum. Thus, this study persuades thepotential of Coelastrella sp. M60 for BPA degradation and suggesting new avenues to remove the emerging contaminants in polluted water bodies and targeted metabolite expression in microalgae.