Abstract
In an attempt to find new class of antibacterial agents, 1-(2-methyl-1,5-diphenyl-1H-pyrrol-3-yl)ethanone (4a –4j) were successfully synthesized from phenacyl bromide ,substituted aryl amine and aetylacetone in the presence of organic base such as DBU promoted in ethanol under reflux. The synthesized compounds were evaluated by spectroscopic techniques such as 1HNMR, 13CNMR and LCMS and elemental analysis. Derivatives were also evaluated for their antibacterial activity.
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