Abstract

Day and Night: Circadian Rhythms in Worms

Highlights

  • Most organisms seem to show ‘‘circadian rhythms’’—cycles of behaviour or gene expression that repeat roughly every 24 hours

  • In a new study published in this issue of PLoS Biology, van der Linden et al used a technique called genome-wide expression profiling to identify genes whose transcripts were rhythmically expressed and exhibited characteristics of being under circadian control

  • The analysis identified three categories of genes with cyclical transcription

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Summary

Introduction

Most organisms seem to show ‘‘circadian rhythms’’—cycles of behaviour or gene expression that repeat roughly every 24 hours. In a new study published in this issue of PLoS Biology, van der Linden et al used a technique called genome-wide expression profiling to identify genes whose transcripts were rhythmically expressed and exhibited characteristics of being under circadian control. By collecting RNA from the adult worms every four hours, they could look for transcripts that were expressed more or less at a particular point in the 24hour cycle.

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