Abstract
In order to evaluate the stability of neonatal parenteral nutrition solution, in this paper, the prescription of neonatal parenteral nutrition solution was investigated and analyzed. The formula of neonatal parenteral nutrition solution used, particularly the one utilized in this study, is commonly used in clinical practice. All the neonatal parenteral nutrition solution required for the test was prepared on the purification workbench in a sterile environment. The time points of stability of parenteral nutrient solution were 0, 12, and 24 hours, respectively, and three parallel samples were taken at each time point. Likewise, to investigate the stability of two kinds of fat milk injection in parenteral nutrition solution of neonates and provide a reference for subsequent experiments and to investigate the influence of electrolyte, amino acid, temperature, pH value, mixing sequence, and the final concentration of glucose on the stability of neonatal parenteral nutrition solution, the stability indexes of neonatal parenteral nutrition liquid mainly include appearance, pH, insoluble particles, fat milk particle size, and particle size distribution. Neonatal parenteral nutrition solution prescriptions from the First Affiliated Hospital of Jinan University, specifically from January to June 2019, were collected and statistically processed. The experimental data were processed by SPSS 19.0 software and data mining technology. The results were expressed as mean ± standard deviation and statistically processed by ANOVA. P < 0.05 was considered statistically significant. The results showed that the stability of neonatal parenteral nutrient solution was influenced by many factors. The formula of neonatal parenteral nutrition solution is generally reasonable, but there are unreasonable phenomena which are needed to be improved further if feasible.
Highlights
Parenteral nutrition (PN) refers to the supply of nutrients required by the body through channels other than the intestinal tract, including calories, vitamins, trace elements, electrolytes, and essential and nonessential amino acids
Newborn parenteral nutrition solution refers to the parenteral nutrition solution specially used for newborn patients, and its quality is directly related to the life safety of newborns. e American Society of Enteral and Parenteral Nutrition recommends that a clinical nutrition team composed of clinicians, pharmacists, nutritionists, and nurses should be formed
The prescription of neonatal parenteral nutrition solution was investigated and analyzed. e formula of neonatal parenteral nutrition solution used, the one which utilized in this study, is commonly used in clinical practice
Summary
Parenteral nutrition (PN) refers to the supply of nutrients required by the body through channels other than the intestinal tract, including calories (fat emulsions and carbohydrates), vitamins, trace elements, electrolytes, and essential and nonessential amino acids. PN can enable patients to maintain a good nutritional status even in the case of a high metabolism or unable to eat normally, improve immunity, promote wound healing, and help the body through the dangerous course of the disease, thereby reducing mortality. E American Society of Enteral and Parenteral Nutrition recommends that a clinical nutrition team composed of clinicians, pharmacists, nutritionists, and nurses should be formed. A reasonable PN formula should meet the needs of patients with malnutrition and consider the risks of supplementing electrolytes, water, multiple nutrients, and minerals to patients. If the PN formula is properly proportioned, it can improve the bioavailability of various nutrients in the body. e total energy required by the body is mainly composed of protein, fat, and sugar, and the latter two mainly constitute nonprotein
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