Abstract

Daphnauranins C–E (compounds 1–3), two sesquiterpenoids and one monoterpenoid were isolated from the roots of Daphne aurantiaca Diels. Daphnauranin C is a 9-O-13 etherified and hydroperoxy-substituted guaiane sesquiterpenoid, daphnauranin D is a guaiane sesquiterpenoid ketal, and daphnauranin E is a monoterpenoid lactone. Their structures were elucidated by comprehensive analyses of MS, 1D NMR, and 2D NMR spectroscopic data. In an anti-feeding activities test, daphnauranins C–E showed activity against male fruit fly with anti-feeding indexes (AI) up to 39.1, 39.2, and 27.8% respectively, at 1 mM.

Highlights

  • With the increase of global population and the changes in food-consumption habits, the food production industry is under unprecedented pressure

  • To seek new insecticide and insect repellent from natural products, we studied the D. aurantiaca roots and found three new compounds, a

  • C15 H22 O4 was determined by the HRESIMS ion at m/z 289.1408 [M + Na]+ (calcd for C15 H22 O4 Na, C15H22O4 was determined by the HRESIMS ion at m/z 289.1408 [M + Na]+ (Supplementary Materials), indicative of five degrees of unsaturation

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Summary

Introduction

With the increase of global population and the changes in food-consumption habits, the food production industry is under unprecedented pressure. One of the biggest threats in agriculture are insects, which cause enormous production losses. To solve this problem there is a need for continuous effective prophylaxis and treatment. Traditional herbs have a long history of use as insecticides and insect repellents [2,3]. Natural products have become a treasury to explore for new insecticides or lead compounds with incomparable excellent structural diversity, ecological safety, biodegradability, and sustainability properties [4,5,6,7]. To seek new insecticide and insect repellent from natural products, we studied the D. aurantiaca roots and found three new compounds, a.

Results and Discussion
General Information
Plant Material
Extraction and Isolation
Anti-Feeding Activity Bioassay
Conclusions
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