Abstract
Introduction: Up to 40% of patients with type 2 Diabetes mellitus (T2DM) develop diabetic nephropathy (DN). This variable proportion depends on several intrinsic factors of the population. The study's objective was to describe the renal functional stage of patients with T2DM and to demonstrate the incidence of occult kidney damage in patients admitted to a provincial reference center for patients with T2DM in Holguín, Cuba. Methods: The present observational, cross-sectional, and prospective study was conducted at the Provincial Diabetic Center in Holguín from March 2019 to March 2021. Cases of patients with T2DM were included. The variables were demographic and clinical (Albuminuria, hyperglycemia, hypertension, proteinuria, hypercholesterolemia, hypertriglyceridemia, hyperuricemia, and fundus). The sample was probabilistic, consisting of 377 cases. Descriptive statistics were used. Results: 537 patients with T2DM were analyzed, including 341 women (63.5%). Patients > 60 years old were 259 (48.2%). The time of diagnosis of T2DM was <1 year in 270 cases (50.3%). 74 cases (13.8%) were patients with already established DN. Patients with obesity and overweight were 74.9%. The presence of albuminuria in grades A2 and A3 was 21.2% (CI95 17.8-24.7%). 60% of cases presented hypertriglyceridemia. High blood pressure occurred in 75.6%. In 79 cases (14.7%), there was diabetic retinopathy. CKD-EPI stage 2 had 254 cases, or 47.3%. Conclusion: Most patients with T2DM (82.1%) have chronic kidney disease in stages 2 to 5. Over half (60%) present Hypertriglyceridemia, obesity, and high blood pressure.
Published Version
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