Abstract
An alcoholic extract of the stems and twigs of Acokanthera longiflora Stapf. showed inhibitory activity against the KB cell culture and was fractionated through a series of partitions and column chromatography to yield three cardenolides: acovenoside A, opposide, and acolongifloroside K. Tests of these and other cardenolides from related species indicated that nearly all of the compounds tested had high in vitro activity but no in vivo activity.
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